{"id":856,"date":"2018-10-02T12:40:15","date_gmt":"2018-10-02T12:40:15","guid":{"rendered":"http:\/\/fishhistopathology.com\/spanish\/?p=856"},"modified":"2020-02-14T15:45:53","modified_gmt":"2020-02-14T18:45:53","slug":"melanosis-muscular","status":"publish","type":"post","link":"https:\/\/fishhistopathology.com\/spa\/?p=856","title":{"rendered":"Melanosis Muscular – Hallazgos macrosc\u00f3picos"},"content":{"rendered":"\n

El t\u00e9rmino melanosis es utilizado para describir la presencia de melanina en zonas anormales. <\/p>\n\n\n\n

\"Figura<\/a>
Figura 1. Salm\u00f3n Atl\u00e1ntico con melanosis muscular.<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n

Se considera que la melanina juega un rol defensivo, ya que es capaz de absorber y neutralizar radicales libres, cationes y potenciales agentes t\u00f3xicos derivados de la degradaci\u00f3n y fagocitosis de material celular.<\/p>\n\n\n\n

\"Figura<\/a>
Figura 2. Salm\u00f3n Atl\u00e1ntico con melanosis muscular debido a fractura.<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n











Las reacciones inflamatorias y la degeneraci\u00f3n tisular en peces \u00f3seos se asocian con la participaci\u00f3n de los melanomacr\u00f3fagos. Los melanomacr\u00f3fagos son macr\u00f3fagos que contienen fragmentos derivados de c\u00e9lulas fagocitadas, principalmente eritrocitos y pigmentos como la melanina, lipofucsina y hemosiderina. <\/p>\n\n\n\n

En salm\u00f3nidos, estos gr\u00e1nulos citoplasm\u00e1ticos son caf\u00e9 oscuro\/negro.<\/p>\n\n\n\n

\"Figura<\/a>
Figura 3. Alev\u00edn de Salm\u00f3n atl\u00e1ntico con melanosis peduncular<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n

En la mayor\u00eda de los peces tele\u00f3steos superiores (no en los salm\u00f3nidos), los melanomacr\u00f3fagos se encuentran dentro de estructuras limitadas por la membrana llamadas centros de melanomacr\u00f3fagos (MMC), que se encuentran m\u00e1s com\u00fanmente en el ri\u00f1\u00f3n y el bazo, pero tambi\u00e9n en otros tejidos en los que hay un alto recambio de c\u00e9lulas, p. Ej. ovario.<\/p>\n\n\n\n

\"Figura<\/a><\/figure><\/div>\n\n\n\n






El pigmento en los melanomacr\u00f3fagos de los tele\u00f3steos superiores suele ser marr\u00f3n dorado, pero puede ser rosado o marr\u00f3n oscuro.<\/p>\n\n\n\n




REFERENCIAS<\/strong><\/p>\n\n\n\n

  • Agius, C., & Roberts, R. J. (2003). Melano\u2010macrophage centres and their role in fish pathology.\u00a0Journal of fish diseases<\/em>,\u00a026<\/em>(9), 499-509.<\/li>
  • Roberts, R. J. (1975). Melanin-containing cells of teleost fish and their relation to disease.\u00a0The pathology of fishes<\/em>,\u00a0399<\/em>, 399-428.<\/li>
  • Passantino, L., Cianciotta, A., Jirillo, F., Carrassi, M., Jirillo, E., & Passantino, G. F. (2005). Lymphoreticular system in fish: erythrocyte-mediated immunomodulation of macrophages contributes to the formation of melanomacrophage centers.\u00a0Immunopharmacology and immunotoxicology<\/em>,\u00a027<\/em>(1), 147-161. <\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"

    El t\u00e9rmino melanosis es utilizado para describir la presencia de melanina en zonas anormales. Se considera que la melanina juega un rol defensivo, ya que es capaz de absorber y neutralizar radicales libres, cationes y potenciales agentes t\u00f3xicos derivados de la degradaci\u00f3n y fagocitosis de material celular. Las reacciones inflamatorias y la degeneraci\u00f3n tisular en peces \u00f3seos se asocian con la participaci\u00f3n de los melanomacr\u00f3fagos. Los melanomacr\u00f3fagos son macr\u00f3fagos que contienen fragmentos derivados de c\u00e9lulas fagocitadas, principalmente eritrocitos y pigmentos como la melanina, lipofucsina y...","protected":false},"author":4,"featured_media":990,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[57,5],"tags":[27,28,29,30,31],"class_list":["post-856","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-piel","category-sistema-musculoesqueletico","tag-melanina","tag-melanocitos","tag-melanomacrofagos","tag-melanosis","tag-melanosomas"],"_links":{"self":[{"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/posts\/856","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=856"}],"version-history":[{"count":10,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/posts\/856\/revisions"}],"predecessor-version":[{"id":1697,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/posts\/856\/revisions\/1697"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=\/wp\/v2\/media\/990"}],"wp:attachment":[{"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=856"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=856"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fishhistopathology.com\/spa\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=856"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}