Infectious salmon anaemia (ISA) is a disease caused by infectious salmon anaemia virus (ISAV), genus Isavirus, family Orthomyxoviridae that affects primarily marine-farmed Atlantic salmon (Salmo salar). Recorded for the first time in 1984 in Norway, it still causes recurrent epidemic outbreaks in Chile. The disease is present in most countries that farm Atlantic salmon: Norway, Scotland, Ireland, Faroe Islands, Canada, USA, and Chile. The virus is adapted to cold-water salmonid fish and has an optimum growth at 15°C. Atlantic salmon is the only species known...