Cardiomyopathy syndrome in Atlantic salmon (CMS) – Histopathology

CMS in ventricle of Atlantic salmon showing severe myocarditis of spongy layer. Note that the compact layer (on the left) is largely unaffected.

Cardiomyopathy syndrome (CMS) is a severe cardiac disease affecting Atlantic salmon characterized by prolonged periods of usually low-level mortalities. The disease was first recognized in farmed Atlantic salmon in Norway in 1985 and subsequently in farmed salmon in the Faroe Islands, Scotland and Ireland. CMS is a transmissible disease that has been causally linked to the Piscine Myocarditis Virus (PMCV), closely allied to the Totiviridae. CMS usually causes mortality in adult or maturing fish after 12 to 18 months in seawater, resulting in substantial economic...

Cardiomyopathy syndrome (CMS) – Gross Pathology

Figure 2. Salmon with CMS. Necrosis in the atrium of this fish has been so severe that it has ruptured. Note that the ventricle appears normal, due only to the fact that the compact layer remains largely unaffected.

Cardiomyopathy syndrome (CMS), is a severe heart disease of Atlantic salmon.  This transmissible condition has been diagnosed in several countries, especially Norway, where it was first reported, but also Scotland, Ireland and the Faroes. It is causally linked to the Piscine Myocarditis Virus (PMCV), closely allied to the Totiviridae. Typically, CMS occurs in the biggest, fastest-growing fish that never go off their feed – indeed their stomach is usually full of pellets when they suddenly die! Brood stock are also susceptible. This disease has an...

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